Centrifugation Equipment
Centrifugation is a process that involves the use of the centrifugal force for the separation of mixtures, used in industry and in laboratory settings. The rate of centrifugation is specified by the acceleration applied to the sample, typically measured in revolutions per minute (RPM).
Chamber Bowl Separators Pharma Biotech
The valuable solids are separated out in the chamber and periodically removed by hand. Separation is executed by reliable, cooled chamber centrifuges. The bowl inserts divides the bowl in two chambers. The product is fed into the center of the rotating bowl through the feed. It flows from the center to the periphery through both chambers, whereas the finer particles are separated out in the outer chamber. The clarifying efficiency remains constant until the chambers are filled with proteins.
Chamber Bowl Separators Pharma Biotech
- Machine driven by a 3-phase AC motor with frequency converter
- Worm wheel gear
- Product connections as TriClamp
- All product-contacting parts are made of high-alloyed stainless steels
- The seals comply with the requirements of the FDA and USP Class VI
- Machine frame and the motor are varnished
- Cooling system
- Throughput capacity from 500 to 1,000 l/h
Clarifiers for Pharma Extraction
Clarifiers for pharma extraction are used in solid-liquid extraction processes with low solid contents (up to approx. 7 % by vol.). Designed in accordance to GMP requirements. Low shear forces are acting on the product by the patented hydrohermetic feed and precise systems for controlled partial ejections. The clarifiers are suitable for fully automatic cleaning-in-place (CIP). Clarifiers cover all processes of liquid-solid extractions, whether in one or more stages on the co-current, counter-current and cross-current principles.
Clarifiers for Pharma Extraction
- Reduced operating costs
- Low solvent requirement
- Higher overall yield by short contact times
- Reduced investment costs by high stage efficiency minimizing the number of stages
- Optimum throughput capacity with minimum space requirement
- Higher overall yield with a significant improvement in substance interchange between the phases by avoiding backmixing
- Higher overall yield qualities
- Higher process security and availability
Centrifuge GMP
Separator skid in the sophisticated compact format for pharmaceutical applications requires little space in the technical centre and, thanks to its sensible design, reliably fulfils even the most demanding technical tasks. You can easily scale the results to any desired production size with no problem. As such, the full functionality of large pharmaceutical centrifuges is available to you in the simplest way, allowing you to concentrate fully on the creative development of your products. Centrifuge GMP is exceptionally easy to operate. The complete preparation, use and maintenance make the smallest possible demands on your team. The system arrives in the technical centre ready for instant use, pre-installed with all connections and control modules in one compact unit that fits even through a 900-mm door.
Centrifuge GMP
- Complete functionality of large pharmaceutical centrifuges
- Cost-effective, compact, time-saving, straightforward
- Production results that can be scaled with no problem
- 20,000 g for reliably separation of the finest particles even with slight density differences
- Three bowl sizes at a flow rate of 15 l/h – 300 l/h
Decanter Centrifuge
Decanter Centrifuge machines are very efficient means of carrying out solid-liquid extraction with a high solids content. Before entering the decanter, the extraction product, which has previously been comminuted, broken down or ground down, is mixed intensively with the extraction agent in a separate mixer. The inlet through which the suspension flows into the decanter is arranged axially in relation to the rotating bowl. The solid-wall bowl has a cylindrical section for efficient clarification of the liquid and a conical section for dewatering the solids. The scroll, which rotates with a slight differential speed relative to the bowl, conveys the solids (extraction residue) to the solids discharge at the conical end of the bowl. The extract is conveyed to the cylindrical end of the bowl where it is discharged via a centripetal pump.
Decanter Centrifuge
- Gas-tight decanters from GEA comply with the test criteria of the strict European ATEX standard.
- The oxygen atmosphere in the decanter is displaced with inert gas and the excess pressure is maintained during operation to assure inert gas blanketing.
- Summation-drive with intelligent kinematics for high differential speeds and torques which enables processing of high solid capacities. High efficiency of the drive since the variable speed motor feeds in energy and does not brake.
- All product-contacting parts are made of high-alloyed stainless steels.
- Depending on the application, the gaskets are made of NBR, FKM or EPDM.
- Chemical cleaning after separation