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Sterile - Pharmaceutical

Sterile dosage forms are those which are free from any microorganisms, dust, fibres, and foreign particles, and should be isotonic. These include parenteral preparations and ophthalmic preparations. Parenteral preparations include Injections, transfusions fluids, sterile suspensions, sterile solids, sterile solutions or emulsions. Ophthalmic preparations include eye drops, eye lotions, eye ointments, eye gels, eye suspensions, contact lens solutions.

Formulation Process #

Pharmaceutical formulation is the multistep process where the active drug is mixed with all other components by considering the factors of particle size, polymorphism, pH, and solubility and becomes the final beneficial medicinal product.

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Handling Process #

Material Handling also known as Conveying is typically a process of transfering raw materials to be processed. As the lifeblood of your company, how your processing line functions has a direct bearing on your bottom line. The success of an entire processing line can depend on the performance and reliability of its material handling systems.

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Homogenization Process #

Similar to Mixing process but Homogenization method uses force (such as turbulence and cavitation) alongside high pressure to create a consistent and uniform sample. Because of its powerful pressure, high pressure homogenization is well-matched for both particle size reduction and cell lysis, which oftentimes requires strong pressure to disrupt cell walls.

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Lyophilization Process #

Lyophilization or freeze drying is a process in which water is removed from a product after it is frozen and placed under a vacuum, allowing the ice to change directly from solid to vapor without passing through a liquid phase.

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Mixing Process #

Mixing is an important part of pharmaceutical production. Operations can include dissolving solids and powders, preparing emulsions, combining raw materials, enabling chemical reactions, and milling active pharmaceutical ingredients (APIs), to name a few.

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Packaging Process #

Once dosage form is in its final form, it must be properly packaged for distribution. Packaging can also come in different forms which determines how products are handled.

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Reduction Process #

Reduction also known as Milling process is done to reduce particle size of solid to physically break down coarse particles to finer ones. Fine drug particulates are especially desired in formulations designed for parenteral, respiratory and transdermal use.

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Spray Drying Process #

Spray drying is a method of producing a dry powder from a liquid or slurry by rapidly drying with a hot gas. This is the preferred method of drying of many thermally-sensitive materials such as foods and pharmaceuticals, or materials which may require extremely consistent, fine, particle size.

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Sterilization Process #

Sterile dosage forms must be isotonic and free from dust, foreign particles, and microorganisms. Sterilization refers to any process that removes, kills, or deactivates all forms of life (in particular referring to microorganisms such as fungi, bacteria, spores, unicellular eukaryotic organisms such as Plasmodium, etc.). After sterilization, an object is referred to as being sterile or aseptic.

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Washing Process #

Manufacturing equipment are also as important as their product. That is why we need to make sure it is always clean before running on production. Usual cleaning methods includes washing, disinfecting and sterilizing.

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